Clinical Research Directory

Proteinuria During Sepsis and Septic Shock: Characterization and Association With ARDS

Sponsor: Centre Hospitalier Intercommunal André Grégoire

Summary

ARDS is a pulmonary edema injury. Among its etiologies, it can be secondary to septic shock. Managing septic shock involves hemodynamic optimization with significant fluid and sodium inputs. Fluid and sodium inputs in ARDS worsen respiratory failure through capillary leakage, and a restrictive input strategy is clinically beneficial (reduced mechanical ventilation duration and ICU stay). Predicting ARDS onset in septic shock allows for optimized fluid and sodium input management, adopting a restrictive rather than liberal approach to minimize deterioration in respiratory function.

Official title: Proteinuria During Sepsis and Septic Shock: Characterization and Association With Acute Respiratory Distress Syndrome

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