Clinical Research Directory

Inclusion Criteria: 1. Written informed consent 2. Diagnosis of an IMID by a rheumatologist with categorisation into one of the following: i. IMID-'higher risk' CVD: individuals who have a risk of developing CVD (based on traditional risk factors and/or IMID-specific factors) but no history of CVD 1. Coronary artery disease (CAD): specifically, a high pre-test probability of CAD based on clinical risk factors (e.g. QRISK3 score ≥10%) and/or elevated biochemical markers (high-sensitivity C-reactive protein ≥2mg/L and/or Lipoprotein(a) ≥70mg/dL) 2. Myopericardial involvement: Specific IMID and/or cardiovascular indicators that place at increased risk e.g. autoantibody associations, presence of peripheral myositis or other major organ involvement; incidental raised serum cardiac biomarkers (troponin and/or NT-pro BNP), on routine testing ii. Incident (new) IMID-CVD: Patients with IMID that present with a new history of CVD <!-- --> 1. ASCVD i. Major adverse cardiovascular events (MACE): \- Non-fatal myocardial infarction. \- Non-fatal stroke of any classification, including reversible focal neurologic \- Defects with imaging evidence of a new cerebral lesion consistent with ischemia or haemorrhage. ii. Other cardiovascular events not accounted for in the MACE-3 composite 2)a)i: \- Hospitalization for unstable angina \- Coronary revascularization \- Hospitalization for heart failure \- Transient Ischemic Attack (TIA) \- Peripheral Vascular Disease (PVD) * Deep vein thrombosis (VTE) and/or pulmonary embolism \[PE\]. 2. Myopericardial involvement: as diagnosed by a cardiology specialist with 'tier 2' cardiovascular imaging and/or other clinical and biochemical criteria in line with usual care iii. Established IMID-CVD a) Patients with IMID and a history of past cardiovascular event as detailed in 2) a) above. b) Patients with a known history of myopericardial involvement as defined above in 2) b) Biological sub-study inclusion criteria * There are no additional inclusion criteria for this sub-study Extended protocol standard CMR sub-study inclusion criteria. * Participants that receive a CMR scan as standard of care Exclusion Criteria: 1. Age less than 18 years 2. Unable to give informed consent Biological sub-study exclusion criteria: \- There are no additional exclusion criteria for this sub-study CMR sub-study exclusion criteria: Standard of care contraindications to: 1. CMR: metal implant eg metal fragments in the eye, pacemaker; claustrophobia; inability to lie flat 2. Magnetic Resonance Imaging (MRI) contrast: renal failure with estimated glomerular filtration rate (eGFR) \<30,