Clinical Research Directory

Inclusion Criteria: 1. Be of either sex with age ≥ 18 years and ≤ 75 years. 2. Hospitalization due to AMI (onset to randomization ≤ 2 weeks), including STEMI and NSTEMI. 3. Meeting the diagnostic criteria for chronic HF, including: (1) Symptoms and/or signs of heart failure; (2) LVEF (Simpson's method) \< 50%, and NT-proBNP ≥ 125pg/mL before enrollment. 4. Patients must be willing to comply with the study protocol and give the informed consent. Exclusion Criteria: 1. Contraindications to cardiopulmonary exercise testing (bicycle ergometer) or 6-minute walking test. 2. Pregnancy, breastfeeding, or planning pregnacy within 1 year. 3. Patients who have undergone mechanical circulatory support (including intra-aortic balloon pump, Impella, ECMO, etc.) or endotracheal intubation. 4. History of viral cardiomytis or non-ischemic cardiomyopathy including dilated cardiomyopathy, hypertrophic cardiomyopathy, perinatal cardiomyopathy, etc. 5. Moderate to severe valvular heart disease or a history of valve replacement. 6. Severe liver dysfunction \[ALT ≥ 3 times the upper limit of normal range or renal dysfunction (eGFR\<60 mL /min/1.73m2)\]. 7. Malignant tumors or other diseases, with expected life expectancy \<1 year. 8. Inability to use smartphones or communicate with the management team for any reason. 9. Enrolled in other clinical trials. 10. Any other clinical conditions unsuitable for this study by the investigator.