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RECRUITING
NCT06479655
PHASE4

Compare the Efficacy and Outcome Between Fentanyl and Morphine as Analgo-sedation in Mechanically Ventilated Patients

Sponsor: Universiti Sains Malaysia

View on ClinicalTrials.gov

Summary

The primary aim of this clinical trial is to compare the effectiveness of fentanyl vs morphine as analgosedation in mechanically ventilated adult patients in the ICU. This study also aims to compare the outcomes of patients between the two groups. The main questions it aims to answer are : 1. Does propofol and fentanyl infusion as analgo-sedation achieve targeted sedation score at 12 and 24 hours compared to propofol and morphine infusion in mechanically ventilated adult patients in the intensive care unit (ICU)? 2. Is there a difference between the proportion of patients requiring rescue sedation dose between the fentanyl and morphine groups?

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

116

Start Date

2024-07-15

Completion Date

2025-12-30

Last Updated

2025-10-06

Healthy Volunteers

No

Conditions

Interventions

DRUG

Fentanyl

Intravenous fentanyl infusion with dilution of 10mcg/ml

DRUG

Morphine

Intravenous morphine infusion with dilution 1mg/ml

Locations (1)

Hospital Universiti Sains Malaysia

Kota Bharu, Kelantan, Malaysia