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Compare the Efficacy and Outcome Between Fentanyl and Morphine as Analgo-sedation in Mechanically Ventilated Patients
Sponsor: Universiti Sains Malaysia
Summary
The primary aim of this clinical trial is to compare the effectiveness of fentanyl vs morphine as analgosedation in mechanically ventilated adult patients in the ICU. This study also aims to compare the outcomes of patients between the two groups. The main questions it aims to answer are : 1. Does propofol and fentanyl infusion as analgo-sedation achieve targeted sedation score at 12 and 24 hours compared to propofol and morphine infusion in mechanically ventilated adult patients in the intensive care unit (ICU)? 2. Is there a difference between the proportion of patients requiring rescue sedation dose between the fentanyl and morphine groups?
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
116
Start Date
2024-07-15
Completion Date
2025-12-30
Last Updated
2025-10-06
Healthy Volunteers
No
Conditions
Interventions
Fentanyl
Intravenous fentanyl infusion with dilution of 10mcg/ml
Morphine
Intravenous morphine infusion with dilution 1mg/ml
Locations (1)
Hospital Universiti Sains Malaysia
Kota Bharu, Kelantan, Malaysia