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Antibiotic Exposure During Pregnancy Affects Infant Gut Microbiota
Sponsor: Peking University People's Hospital
Summary
Based on a prospective birth cohort, the investigators will collect biological samples from participants including pregnant women and newborns, to measure the gut microbial diversity and metabolites of newborns. These results systematically evaluate the effects of antibiotic exposure on the structure and function of gut microbiota. The project can reveal the effects of antibiotic exposure on the growth and development of gut microbiota in early life.
Key Details
Gender
All
Age Range
1 Day - 12 Months
Study Type
OBSERVATIONAL
Enrollment
450
Start Date
2023-06-25
Completion Date
2024-08-30
Last Updated
2024-07-24
Healthy Volunteers
Yes
Interventions
antibiotic treatment
AT: Mother-infant cohort with antibiotic treatment group CS: Mother-infant cohort (Prophylactic antibiotics therapy) ND: Mother-infant cohort (Natural delivery)
Locations (1)
The Peking University People's Hospital
Beijing, China