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Mechanical Ventilation on Hippocampus
Sponsor: Beijing Sanbo Brain Hospital
Summary
Ventilator-associated brain injury (VABI) frequently occurs in ICU patients. Although animal studies indicate the hippocampus as a key target of VABI, its relevance in human patients remains uncertain. In this study, the investigators aim to monitor hippocampal EEG activity during the weaning process of patients off mechanical ventilation, and also exploring the coupling between breathing patterns and hippocampal activity.
Official title: Impact of Mechanical Ventilation on Hippocampal Oscillation and Respiratory-hippocampus Coupling
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
20
Start Date
2024-05-08
Completion Date
2025-06-01
Last Updated
2024-08-09
Healthy Volunteers
No
Interventions
Mechanical ventilation
After replacing the electrode, we'll monitor the EEG activity of the hippocampus and other cortex regions while weaning off mechanical ventilation.
Locations (1)
Beijing Sanbo Brain Hospital, Capital Medical University
Beijing, Beijing Municipality, China