Clinical Research Directory

Inclusion Criteria: * Patients ≥ 18 years old, men or women. * Planned primary resection due to colorectal neoplasia (cancer or benign polyps) of the sigmoid colon or rectum (above the peritoneal reflection) that require high anterior resection as the procedure of choice. * Patient indicated to elective minimally invasive sigmoid or high rectal resection. Exclusion Criteria: * Patients with pre-existing health conditions requiring surgery, such as intestinal obstruction or perforation, local or systemic infections, peritonitis, or intestinal ischemia. * Patients with preoperative evidence of distal metastasis. * Patients with documented intestinal or anal stenosis or other obstructions distal to the anastomosis. * Patients who received radiation therapy to organs in abdomen or pelvis unrelated to current colorectal condition. * Patients indicated to defunctioning ileostomy (intention to treat). * Any condition that, in the opinion of the investigator, may interfere with the study conduction. In particular, any condition which can cause significant alteration of colonic wall thickness such as chronic and repeated infection which may impair the use of C-REX.