Clinical Research Directory
Browse clinical research sites, groups, and studies.
Summary
Stage 2 Type 1 Diabates (T1D) is an early stage of T1D characterized by dysglycemia but not yet leading to clinical symptoms. Progression of the disease to Stage 3 (clinical T1D), leads to overt hyperglycemia requiring eventually exogenous insulin. TZIELD® (teplizumab-mzwv) has been approved to delay onset of stage 3 T1D, by the United States (US) Food and Drug Administration (FDA) for adults and children aged 8 years and older with Stage 2 T1D. The purpose of this study is to collect general information on patients with stage 2 T1D and further information on the long-term effects of TZIELD® in patients with Stage 2 T1D, treated as per standard of care.
Official title: An Observational, Long-term Safety Study of TZIELD® (Teplizumab-mzwv) in Patients With Stage 2 Type 1 Diabetes
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2024-09-27
Completion Date
2037-01-15
Last Updated
2026-02-17
Healthy Volunteers
No
Conditions
Interventions
TZIELD (teplizumab-mzwv)
This study will not administer any treatment, only observe the treatment as prescribed in real-world clinical practice.
Locations (34)
University of California Los Angeles Health- Site Number : 8400020
Los Angeles, California, United States
University of California San Francisco - Mission Bay- Site Number : 8400005
San Francisco, California, United States
University of Colorado Hospital- Site Number : 8400026
Aurora, Colorado, United States
Yale University School of Medicine- Site Number : 8400025
New Haven, Connecticut, United States
University of Florida Health- Site Number : 8400035
Gainesville, Florida, United States
Nemours Children's Speciality Care- Jacksonville- Site Number : 8400006
Jacksonville, Florida, United States
University of South Florida- Site Number : 8400022
Tampa, Florida, United States
Midtown Medical Center - Columbus- Site Number : 8400013
Columbus, Georgia, United States
University of Chicago Medical Center- Site Number : 8400017
Chicago, Illinois, United States
Indiana University Health Riley Hospital for Children- Site Number : 8400004
Indianapolis, Indiana, United States
Norton Brownsboro Hospital- Site Number : 8400030
Louisville, Kentucky, United States
Johns Hopkins School of Medicine- Site Number : 8400031
Baltimore, Maryland, United States
University of Michigan Health System - Ann Arbor- Site Number : 8400028
Ann Arbor, Michigan, United States
Associated Endocrinologists, PC- Site Number : 8400039
Farmington Hills, Michigan, United States
Corewell Health - Grand Rapids - Michigan Street Northeast- Site Number : 8400009
Grand Rapids, Michigan, United States
Mayo Clinic- Site Number : 8400010
Rochester, Minnesota, United States
Children's Mercy Adelle Hall Campus- Site Number : 8400014
Kansas City, Missouri, United States
Women & Children's Hospital of Buffalo- Site Number : 8400018
Buffalo, New York, United States
Feinstein Institute for Medical Research (Northwell)- Site Number : 8400016
Manhasset, New York, United States
Ten's Medical PC- Site Number : 8400027
Staten Island, New York, United States
SUNY Upstate Medical University - Syracuse- Site Number : 8400007
Syracuse, New York, United States
UNC Children's Hospital- Site Number : 8400008
Chapel Hill, North Carolina, United States
Cincinnati Children's Hospital Medical Center- Site Number : 8400024
Cincinnati, Ohio, United States
Rainbow Babies And Children's Hospital- Site Number : 8400011
Cleveland, Ohio, United States
The Ohio State University- Site Number : 8400032
Columbus, Ohio, United States
Hospital of The University of Pennsylvania- Site Number : 8400021
Philadelphia, Pennsylvania, United States
The Children's Hospital of Philadelphia- Site Number : 8400029
Philadelphia, Pennsylvania, United States
AM Diabetes & Endocrinology Center- Site Number : 8400012
Bartlett, Tennessee, United States
Vanderbilt University Medical Center- Site Number : 8400023
Nashville, Tennessee, United States
Texas Diabetes & Endocrinology - Austin - North Mopac Expressway- Site Number : 8400040
Austin, Texas, United States
University of Texas - Southwestern Medical Center- Site Number : 8400003
Dallas, Texas, United States
Texas Children's Hospital- Site Number : 8400002
Houston, Texas, United States
University of Utah Health Hospital- Site Number : 8400019
Salt Lake City, Utah, United States
United BioSource Corporation- Site Number : 8400001
Morgantown, West Virginia, United States