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Dysfunction of Olfaction After COVID-19 Infection: Morphological and Histomolecular Investigation
Sponsor: Universitaire Ziekenhuizen KU Leuven
Summary
Investigation of the mechanisms of persistent SARS-CoV-2 associated olfactory dysfunction (OD) in patients with well-documented olfactory function. The investigators plan to collect olfactory cleft biopsies and cytobrushes in COVID-19 patients and controls.
Official title: Dysfunction of Olfaction After SARS-CoV-2 Infection: Morphological and Histomolecular Investigation of Olfactory Cleft Biopsies and Cytobrushes
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
240
Start Date
2024-01-24
Completion Date
2026-12-31
Last Updated
2025-03-12
Healthy Volunteers
No
Conditions
Interventions
Biopsy and Cytobrush
Collection of olfactory cleft biopsies and cytobrushes
Locations (7)
Cliniques Universitaires Saint-Luc
Brussels, Brussels Capital, Belgium
UZ/KU Leuven
Leuven, Vlaams-Brabant, Belgium
AZ Sint-Jan Brugge
Bruges, West-Vlaanderen, Belgium
University Hospital Carl Gustav Carus
Dresden, Dresden, Germany
Max Planck Research Unit for Neurogenetics
Frankfurt am Main, Frankfurt, Germany
Hôpitaux Universitaires de Genève
Geneva, Canton of Geneva, Switzerland
University of Zurich and University Hospital Zurich
Zurich, Canton of Zurich, Switzerland