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Pain Control After Lumbar Spine Fusion
Sponsor: Rothman Institute Orthopaedics
Summary
The purpose of this randomized controlled trial is to determine if patients who receive non-steroidal anti-inflammatory medications (NSAIDs) following elective lumbar spinal fusion have increased rates of symptomatic nonunion requiring revision spinal surgery at two-years follow-up, compared to those who do not receive NSAIDs.
Official title: Randomized Controlled Trial of Postoperative Inpatient Ketorolac and Outpatient Naproxen Use Following Elective Lumbar Spine Fusion
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
428
Start Date
2024-06-28
Completion Date
2025-06-30
Last Updated
2024-07-03
Healthy Volunteers
Yes
Interventions
Naproxen 500 Mg
participants will receive Naproxen (500 mg) to take for 7 days after surgery as needed
Ketorolac
participants will receive Ketorolac (15 mg) immediately after surgery
OxyCODONE 5 mg Oral Tablet
participants will receive OxyCODONE (5 mg) to take for 7 days after surgery as needed
Metaxalone 800 MG
participants will receive Metaxalone (800 MG) to take for 7 days after surgery as needed
Locations (1)
Rothman Orthopaedic Institute
Philadelphia, Pennsylvania, United States