Clinical Research Directory

Inclusion Criteria: ARDS patients \- Exclusion Criteria:Patients with any of the following criteria were excluded: * History of emphysema, asthma, pneumothorax, or active bronchopulmonary fistula. * Severe instability at the time of the study defined by at least one of the following indicators: SaO2 ≤ 90%, shock requiring \> 0.5 γ/kg/min of noradrenaline, complex arrhythmia, myocardial ischemia, intracranial hypertension refractory despite first-line measures. * Esophageal pathology contraindicating esophageal balloon placement (esophageal varices, stenosis, trauma or esophageal surgery, tumor) and/or hematemesis. * Severe coagulopathy (platelet count \<20,000/mm3 or INR \>4. * Inability to undergo computed tomography: morbid obesity (\>170 kg) or abdominal circumference \>200 cm. * Patients with do-not-resuscitate orders and pregnant women. * Participation in another research study in the last 30 days.