Clinical Research Directory

Inclusion Criteria: 1. Male or female, who randomized into Sham control group and withdrew from CTP-BM-22-01 Study (i.e. main study) due to lack of efficacy. 2. Completed 14-day evaluation in main study. 3. Will provide completed and signed written informed consents. Exclusion Criteria: 1. Pregnant women. 2. Subjects who do not meet any of the inclusion criteria in CTP-BM-22-01 Study (i.e. main study) after re-evaluation. 3. Determined by the investigator to be not suitable for the conduct of the study for any other reasons.