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Preoperative Use of Pantoprazole for Prevention of Post Operative Nausea and Vomiting in Gynecologic Surgery
Sponsor: United States Naval Medical Center, Portsmouth
Summary
The goal of this clinical trial is to see if pantoprazole (a proton pump inhibitor used for acid reflux/heart burn) can reduce nausea and vomiting after gynecologic surgery in women between the ages of 18 and 79. Researchers will compare a placebo to the active medication. Participants will be asked to take three pills around their surgery, two taken before and one taken the night after.
Key Details
Gender
FEMALE
Age Range
18 Years - 79 Years
Study Type
INTERVENTIONAL
Enrollment
132
Start Date
2022-08-26
Completion Date
2026-12
Last Updated
2025-05-21
Healthy Volunteers
Yes
Conditions
Interventions
pantoprazole
Pantoprazole 40mg given the night before surgery, 2 hours prior to surgery, and the evening after surgery.
Placebo
Placebo given the night before surgery, 2 hours prior to surgery, and the evening after surgery.
Locations (1)
Naval Medical Center Portsmouth
Portsmouth, Virginia, United States