Clinical Research Directory

Inclusion Criteria: * Phase 1- All individuals (50-65yrs) consenting to participate will be included. Phase 3- Inclusion for multidomain intervention * Individuals between 50-65 years old, willing to participate and comply with all the study evaluation and intervention procedures * CAIDE (Cardiovascular Risk Factors, Aging and Dementia) Dementia Risk Score of 6 points or higher * Those identified to have mild cognitive impairment in phase 1 screening Exclusion Criteria: • Phase 1- Those who are unable to respond, critically ill and having a physician diagnosed dementia report will be excluded. Phase 3- Exclusion for multidomain intervention * Geriatric Depression Scale ≥ 9 * Dementia * Disorders that may affect safe involvement in the intervention (eg, malignancy, symptomatic cardiovascular disease, Large vessel stroke in the past two years, History of transient ischemia attack (TIA) or small vessel stroke in the last 6 months, revascularization within 1 year previously, severe loss of vision, hearing, or communicative ability) * Coincident participation in another intervention trial. * Recent (\< 3 months) bone fracture. * History of hip fracture, joint replacement, or spinal surgery in the last 6 months * Clinically significant abnormalities in laboratory blood tests as per judgment of the site study clinician.