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Strokectomy in Malignant Cerebral Media Infarction
Sponsor: University of Rostock
Summary
Decompressive hemicraniectomy (DC) is the standard procedure and life saving measure in case of malignant middle cerebral artery (MCA) infarction. However, there have been several studies reporting the neuroinflammatory cascade based on the necrotic tissue as one of the leading cause for the secondary brain damage, wherefore, strokectomy with resection of necrotic tissue has been proposed in some case series as an alternative surgical option. Thus, the aim of this study is to perform a pilot study by including patients with malignant MCA infarction and to check the feasibility of this specific surgical treatment.
Official title: Strokectomy in Malignant Cerebral Media Infarction: A Pilot Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
10
Start Date
2024-06-15
Completion Date
2025-06-30
Last Updated
2024-07-08
Healthy Volunteers
No
Conditions
Interventions
Strokectomy/Necrosectomy
After obtaining CT-/MRT-perfusion, the infarcted area (e.g. infarct core) of malignant MCA-infarction is localized. By using the neuronavigation, surgical resection of necrotic tissue is performed in a non-eloquent area until the space occupying effect is released. At the end of the surgery, the bone flap is reinserted and fixated.
Locations (1)
University Medical Center Rostock
Rostock, Mecklenburg-Vorpommern, Germany