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Predicting Postoperative Chemotherapy Efficacy in Patients With Esophageal Squamous Cell Carcinoma
Sponsor: City of Hope Medical Center
Summary
Esophageal cancer remains a disease with a poor prognosis. Chemotherapy is an important part of its treatment, but there are cases in which chemotherapy is ineffective. The investigators aim to develop a model to predict the response to chemotherapy by DNA methylation of preoperative biopsy specimens to identify the chemotherapy ineffective group.
Official title: Predicting Postoperative Chemotherapy Efficacy in Patients With Esophageal Squamous Cell Carcinoma by Biopsy Specimens.
Key Details
Gender
All
Age Range
20 Years - Any
Study Type
OBSERVATIONAL
Enrollment
150
Start Date
2004-06-01
Completion Date
2026-06-18
Last Updated
2025-07-11
Healthy Volunteers
No
Interventions
Fluoro Uracil
Esophageal cancer chemotherapy（First line treatment)
Locations (1)
Yamanashi Universiy
Chūō, Yamanashi, Japan