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Biometric Changes After Intervention of Anterior Chamber Angle : an Observational Study
Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University
Summary
The drainage angle in the anterior chamber of the eye mediates the outflow of aqueous humor, and pathological changes here can lead to high intraocular pressure and glaucoma. Minimally invasive glaucoma surgery, particularly angle surgery, has advanced recently, allowing clear visualization of angle structures like the trabecular meshwork and Schlemm's canal using surgical goniolens. Techniques for angle intervention include widening the angle, reopening closed angles, and rebuilding outflow pathways using methods such as laser peripheral iridotomy, Argon laser peripheral iridoplasty, and mechanical separation of adhered tissues. Our research team plans to conduct imaging studies to track the healing of angle tissues post-surgery, aiming to support innovation and standardization of minimally invasive angle surgery.
Key Details
Gender
All
Age Range
30 Years - 85 Years
Study Type
OBSERVATIONAL
Enrollment
300
Start Date
2023-12-01
Completion Date
2025-12-30
Last Updated
2025-12-12
Healthy Volunteers
Not specified
Conditions
Interventions
various types of angle interventions
procedures include laser peripheral iridotomy (LPI) to relieve pupillary tissue and deepen peripheral anterior chamber depth, Argon laser peripheral iridoplasty (ALPIp) to stimulate iris contraction and widen the angle, and mechanical separation of adhered angle tissues using instruments like goniosynechialysis hooks or iris repositor. Ab interno goniotomy using instruments like retina hooks, trabeculectomy hooks, or cannulas are used to incise trabecular meshwork and Schlemm's canal walls to enhance aqueous humor outflow.
Locations (1)
Zhongshan ophthalmic center
Guangzhou, Guangdong, China