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Clinical Efficacy of Prophylactic Intravenous Neostigmine and Atropine in Preventing Post-Dural Puncture Headache Among Parturient Undergoing Spinal Anesthesia for Cesarean Section: A Double-blind Randomized Placebo-controlled Trial
Sponsor: Minia University
Summary
Post dural puncture headache is a distressing issue, many measures tried to treat symptoms but few delt with prevention.
Key Details
Gender
FEMALE
Age Range
18 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
180
Start Date
2024-07-15
Completion Date
2025-01-16
Last Updated
2024-07-16
Healthy Volunteers
No
Conditions
Interventions
intravenous 50 mL of saline injection of 0.9% after umbilical cord clamping.
intravenous 50 mL of saline injection of 0.9% after umbilical cord clamping.
Neostigmine 20μg/kg (Neostigmine Methylsulphate 0.5 mg, Amriya Pharm.Ind.) and atropine 0.01 mg/kg (diluted in 50 ml saline; 0.9% for 10 min) following umbilical cord clamping.
Neostigmine 20μg/kg (Neostigmine Methylsulphate 0.5 mg, Amriya Pharm.Ind.) and atropine 0.01 mg/kg (diluted in 50 ml saline; 0.9% for 10 min) following umbilical cord clamping.