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RECRUITING
NCT06496191
NA

FMT for Alcohol Use Disorder in Cirrhotics.

Sponsor: Institute of Liver and Biliary Sciences, India

View on ClinicalTrials.gov

Summary

* Title "FMT for Alcohol Use Disorder in cirrhotics: A Randomized Controlled Trial" * The aim of the study is to study the efficacy of Fecal microbiota transplantation in patients with Alcohol liver disease over a 6 month duration without liver related side effects. The project will be conducted at ILBS over the period of 1 year. * The concept is to test the efficacy of FMT in alcohol related cirrhotics by its effect on achieving and maintaining abstinence and in reducing lapses and relapses. Thereby reducing the progression of alcoholic liver disease as continued ethanol consumption is an important predictor in increasing overall morbidity and mortality.

Official title: FMT for Alcohol Use Disorder in Cirrhotics: A Randomized Controlled Trial.

Key Details

Gender

All

Age Range

18 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

54

Start Date

2024-07-27

Completion Date

2025-06-30

Last Updated

2024-07-30

Healthy Volunteers

No

Conditions

Interventions

BIOLOGICAL

FMT

\- Single dose (30gm/90ml) of FMT will be given via upper GI gastroduodenoscope at D4

OTHER

SMT

Baclofen + AUD counselling

OTHER

Placebo

Placebo identical to the FMT arm.

Locations (1)

Institute of Liver & Biliary Sciences (ILBS)

New Delhi, National Capital Territory of Delhi, India