Clinical Research Directory

Inclusion Criteria: * Age : 6 - 18 years old. * All children diagnosed by Primary monosymptomatic nocturnal enuresis in this age group. Exclusion Criteria: * Secondary nocturnal enuresis (child who has been continent for at least 6 months before the onset of bedwetting ). * congenital anomalies (Posterior urethral valve , ectopic ureter , ectopia vesica ,…) * history of previous lower urinary tract surgery (Multiple hypospadias surgeries ,…, ) * neurogenic bladder (as underactive bladder ).and urge incontinence. * presence of post-void residual urine greater than 20% of functional bladder capacity. * history or evidence of disorders in other organs such as (cardiovascular system disease), liver , psychological problems , evident allergic reaction to both medication.