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RECRUITING
NCT06498505
PHASE4

HighCycle: Effect of Acetazolamide on Pulmonary Artery Pressure in Women Compared to Men

Sponsor: University of Zurich

View on ClinicalTrials.gov

Summary

Randomized clinical trial evaluating the effect of acetazolamide on pulmonary artery pressure in women compared to men travelling to 3600 m.

Official title: HighCycle: Effect of Acetazolamide on Pulmonary Artery Pressure in Women Compared to Men. A Randomized, Placebo-Controlled, Double-Blind Parallel Trial.

Key Details

Gender

All

Age Range

18 Years - 44 Years

Study Type

INTERVENTIONAL

Enrollment

270

Start Date

2024-07-15

Completion Date

2025-12-31

Last Updated

2025-06-13

Healthy Volunteers

Yes

Conditions

Interventions

DRUG

Acetazolamide

Administration of 1x125mg acetazolamide in the morning, 1x125mg in the evening, starting 24 hours before departure to 3600 m.

DRUG

Placebo

Administration of equally looking placebo capsules in the morning and in the evening, starting 24 hours before departure to 3600 m.

Locations (1)

National Center for Cardiology and Internal Medicine

Bishkek, Gorod Bishkek, Kyrgyzstan