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RECRUITING
NCT06499584
NA

Study of the Fine Structure and Temporal Envelope of the Human Cochlea in Response to Human Vocalizations

Sponsor: CHU de Reims

View on ClinicalTrials.gov

Summary

In humans, surface electrophysiological recordings of the cochlear nerve in response to a sound stimulus provide information about the cochlear's ability to encode sound. Depending on the stimulus, the fine structure and temporal envelope of the signal will vary, allowing us to determine its characteristics. By phenotyping patients before surgery using subjective and objective audiometric tests, it will be possible to isolate for each patient the moment when the fine structure disappears and when the temporal envelope is effective.

Official title: The Functional Role of Cochlear Synaptopathy for Speech Coding in the Brain

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2023-03-21

Completion Date

2027-12

Last Updated

2024-07-12

Healthy Volunteers

No

Interventions

PROCEDURE

near field recording of human auditory nerve activity during retro sigmoid approach with contact electrode

During surgery using a retro-sigmoid approach in the cerebellopontine angle (microvascular decompression), near-field recording of human auditory nerve activity using a contact electrode is performed on patients with normal or impaired hearing threshold. Each patient is explored preoperatively by hearing tests. During the surgery, stimuli are delivered.

Locations (1)

Damien JOLLY

Reims, France