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Study of the Fine Structure and Temporal Envelope of the Human Cochlea in Response to Human Vocalizations
Sponsor: CHU de Reims
Summary
In humans, surface electrophysiological recordings of the cochlear nerve in response to a sound stimulus provide information about the cochlear's ability to encode sound. Depending on the stimulus, the fine structure and temporal envelope of the signal will vary, allowing us to determine its characteristics. By phenotyping patients before surgery using subjective and objective audiometric tests, it will be possible to isolate for each patient the moment when the fine structure disappears and when the temporal envelope is effective.
Official title: The Functional Role of Cochlear Synaptopathy for Speech Coding in the Brain
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2023-03-21
Completion Date
2027-12
Last Updated
2024-07-12
Healthy Volunteers
No
Interventions
near field recording of human auditory nerve activity during retro sigmoid approach with contact electrode
During surgery using a retro-sigmoid approach in the cerebellopontine angle (microvascular decompression), near-field recording of human auditory nerve activity using a contact electrode is performed on patients with normal or impaired hearing threshold. Each patient is explored preoperatively by hearing tests. During the surgery, stimuli are delivered.
Locations (1)
Damien JOLLY
Reims, France