Clinical Research Directory
Browse clinical research sites, groups, and studies.
Long Term Outcomes After Vestibular Implantation
Sponsor: Johns Hopkins University
Summary
Although cochlear implants can restore hearing to individuals who have lost cochlear hair cell function, there is no widely available, adequately effective treatment for individuals suffering chronic imbalance, postural instability and unsteady vision due to bilateral vestibular hypofunction. Prior research focused on ototoxic cases has demonstrated that electrical stimulation of the vestibular nerve via a chronically implanted multichannel vestibular implant can partially restore vestibular reflexes that normally maintain steady posture and vision; improve performance on objective measures of postural stability and gait; and improve patient-reported disability and health-related quality of life. This single-arm open-label study extends that research to evaluate outcomes for up to 8 individuals with non-ototoxic bilateral vestibular hypofunction, yielding a total of fifteen adults (age 22-90 years at time of enrollment) divided as equally as possible between ototoxic and non-ototoxic cases.
Key Details
Gender
All
Age Range
22 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
32
Start Date
2024-12-01
Completion Date
2029-12
Last Updated
2026-03-09
Healthy Volunteers
No
Conditions
Interventions
Labyrinth Devices MVI™ Multichannel Vestibular Implant System
Continuously motion-modulated stimulation delivered by a vestibular implant already implanted under a prior study protocol (Labyrinth Devices MVI™ Multichannel Vestibular Implant System)
Locations (1)
Johns Hopkins School of Medicine
Baltimore, Maryland, United States