Clinical Research Directory

Inclusion Criteria: * 1\. Age 7-45 years 2. Able to wear multi-channel physiological measurement devices and cooperate with experimental procedures. 3\. Binocular? spherical power between -0.50 to -5.00 diopters, and cylinder power no more than -1.50 diopters. 4\. Voluntarily participate in this study with informed consent form signed. Exclusion Criteria: * 1\. History of diseases affecting autonomic nervous system function, such as depression and anxiety. 2\. History of eye diseases such as strabismus, amblyopia, keratitis, and glaucoma, which are unsuitable for eye movement test. 3\. History of major systemic diseases or surgeries such as cranial surgery, myocardial infarction, or stroke. 4\. Systemic medication history that may affect autonomic nervous system function, including but not limited to antidepressants, antihistamines, anticholinergics, antipsychotics, and sedative-hypnotic drugs like diazepam or lorazepam. 5\. Use of eyedrops such as mydriatics or miotics that will affect pupil size. 6. Having difficulty in understanding and cooperating with the trial, such as those with disabilities, communication barriers, or those unable to undertake examinations. 7\. Other contradictions that the physician may consider inappropriate for enrolment.