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ACTIVE NOT RECRUITING
NCT06503601
The Impact of Genetic Polymorphism on the Echocardiographic Parameters and Cardiac Fibrosis Markers in Response to Empagliflozin Treatment Among Patients With Heart Failure
Sponsor: Ain Shams University
View on ClinicalTrials.gov
Summary
It is important to assess the implications of genetic variants of the TGF-β1 gene in patients with HFrEF and the association of this polymorphism with treatment response to SGLT2I. Therefore, by correlating the pharmacogenetics hand in hand with the mechanistic markers involved in the pathogenesis of HF, this can aid in the development of individualized, therapeutic strategies and improve the patient's drug response.
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
92
Start Date
2023-07-30
Completion Date
2025-10-01
Last Updated
2024-07-16
Healthy Volunteers
No
Conditions
Locations (1)
Ain shams university
Cairo, Egypt