Clinical Research Directory

Inclusion Criteria: * Vital mandibular molar teeth with mature apices. * Teeth that respond positively to cold testing. * Teeth without any signs of necrosis including sinus tract or swelling. * Teeth with caries extending ≥ 2/3 of dentine or exposing the pulp. * Teeth with symptomatic irreversible pulpitis with/without apical periodontitis. * Teeth without periodontal diseases or mobility. * Teeth without root resorption, detectable pulp chamber and root canal calcification or history of trauma. * Patients from both genders with age range from 20 to 45 years old. * Patients with good or moderate oral hygiene and without any systemic diseases. Exclusion Criteria: Pre-operative criteria: * Non-vital teeth. * Teeth with irreversible pulpitis with apical periodontitis. * Teeth with immature apices. * Teeth with Periodontal disease or mobility grade II or III. * Teeth that are badly decayed and need post and core placement. * Patients refused to continue treatment procedures or refuse to commit to periodic follow-up sessions. * Non-restorable teeth. Intra-operative criteria: * If hemostasis could not be achieved within 6 minutes after full pulpotomy. * Teeth with partial necrosis. * No bleeding after access cavity preparation. Post-operative criteria: * presence of Swelling. * presence of Sinus tract. * Pain on percussion after the end of the first week. * Pain with palpation. * Pain on biting after the end of first week. * Mobility of the tooth. * Fracture of tooth structure that renders the tooth non-restorable. * Fracture of the restoration during the evaluation. * Probing depth more than 3 mm.