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ENROLLING BY INVITATION
NCT06505356
NA

Characterization of Microbiological and Genetic Features in Prostate Cancer and Their Association with Disease Stage

Sponsor: Edgaras Burzinskis

View on ClinicalTrials.gov

Summary

1. Identify the local inflammatory response in prostate tissue and the systemic response in the blood of patients with prostate cancer, depending on the stage of the disease, and evaluate their prognostic value. 2. Identify the spectrum of microorganisms and antibiotic resistance in patients with prostate cancer prior to prostate biopsy, and assess the risk of complications when using Ciprofloxacin and Fosfomycin. 3. Determine the significance of GAS5, JAZF1, and CTBP2 gene polymorphisms in the development of prostate cancer. 4. Evaluate the association of a specific gene polymorphism with the clinical course of the disease in patients with prostate cancer.

Official title: Characterization of Microbiological and Genetic Features in Prostate Cancer Patients and Their Associations with Disease Stage and Clinical Presentation

Key Details

Gender

MALE

Age Range

18 Years - 100 Years

Study Type

INTERVENTIONAL

Enrollment

400

Start Date

2024-09-01

Completion Date

2028-08-30

Last Updated

2025-03-13

Healthy Volunteers

No

Interventions

PROCEDURE

Prostate biopsy

Transrectal prostate biopsy

Locations (1)

Lithuanian University of Health Sciences

Kaunas, Lithuania