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Characterization of Microbiological and Genetic Features in Prostate Cancer and Their Association with Disease Stage
Sponsor: Edgaras Burzinskis
Summary
1. Identify the local inflammatory response in prostate tissue and the systemic response in the blood of patients with prostate cancer, depending on the stage of the disease, and evaluate their prognostic value. 2. Identify the spectrum of microorganisms and antibiotic resistance in patients with prostate cancer prior to prostate biopsy, and assess the risk of complications when using Ciprofloxacin and Fosfomycin. 3. Determine the significance of GAS5, JAZF1, and CTBP2 gene polymorphisms in the development of prostate cancer. 4. Evaluate the association of a specific gene polymorphism with the clinical course of the disease in patients with prostate cancer.
Official title: Characterization of Microbiological and Genetic Features in Prostate Cancer Patients and Their Associations with Disease Stage and Clinical Presentation
Key Details
Gender
MALE
Age Range
18 Years - 100 Years
Study Type
INTERVENTIONAL
Enrollment
400
Start Date
2024-09-01
Completion Date
2028-08-30
Last Updated
2025-03-13
Healthy Volunteers
No
Conditions
Interventions
Prostate biopsy
Transrectal prostate biopsy
Locations (1)
Lithuanian University of Health Sciences
Kaunas, Lithuania