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Additive Effects of Clonidine Used in Propofol Sedation in Colonoscopy
Sponsor: Tanta University
Summary
The objective of this study was to compare safety, satisfaction, and efficiency outcomes of propofol versus propofol with clonidine in patients undergoing colonoscopy.
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
62
Start Date
2024-07-20
Completion Date
2024-09-01
Last Updated
2024-07-23
Healthy Volunteers
No
Conditions
Interventions
Propofol
Continuous propofol infusion will be given with syringe pump for maintenance, with the initial rate set at 25-75 mic/kg/min IV during the first 10-15 min. To avoid administering sedatives at rates greater than clinically necessary, infusion rates will be gradually titrated to 25-50 mic/kg/min and regulated with the clinical response, with an onset of peak drug action expected to occur within 2 min.
Propofol combined with clonidine
Patients will receive 2 μg/kg of clonidine for injection intravenously 30 min before induction of sedation, administered over 10 min.
Locations (1)
Tanta University
Tanta, El-Gharbia, Egypt