Clinical Research Directory

Inclusion Criteria: * Patients must be diagnosed with COPD and/or asthma and/or pulmonary neoplasm and/or secondary pulmonary, pleural or mediastinal determinations, suspected or confirmed, according to ICD-10. * Patients will be included regardless of the type of hospitalization, continuous or day. * The existence of freely expressed consent, carried out according to Ethics standards professional (from the observation sheet). For stage 2 * The use of HRCT images, in DICOM format, with a maximum cup thickness of 1.5 mm and with an average of 250 cups; no image acquisition errors; * Imaging monitoring at a time interval;. * Respiratory function evaluation data available: spirometry +/- the factor of gaseous diffusion (DLco); Exclusion Criteria: For both stages: \- Patients who do not have a stable real domicile (eg social cases) or are not from the Timis county For stage 2 * Patients who do not have HRCT images available or cannot be followed. * Patients who have insufficient quality HRCT images. * Patients who have a history of lung surgery. * Patients who have a history of allergies to contrast agents used in imaging HRCT.