Clinical Research Directory
Browse clinical research sites, groups, and studies.
Developing a Treatment Clustering System for Obstructive Sleep Apnea Using Polysomnographic Physiological Signals
Sponsor: National Cheng-Kung University Hospital
Summary
Obstructive sleep apnea syndrome (OSA) is marked by repeated upper airway obstructions during sleep, affecting approximately 14% of men and 5% of women aged 30-70 years. However, precise clinical prediction tools for selecting optimal treatment strategies are lacking. This study aims to develop an automated treatment clustering system using artificial intelligence to classify patients based on etiology into (i) anatomical factors, (ii) reduced muscle responsiveness, and (iii) other non-anatomical factors. This system will analyze physiological sleep assessments, such as electromyography (EMG) and pneumotachographs, from a retrospective polysomnography (PSG) database. Cross-validation will be conducted on new OSA patients undergoing various management strategies, including surgical intervention, CPAP therapy, and oropharyngeal training (delivered face-to-face or via telerehabilitation). This system aims to enhance clinicians' ability to predict treatment success rates and improve patient outcomes.
Key Details
Gender
All
Age Range
20 Years - Any
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2024-07-30
Completion Date
2026-05-01
Last Updated
2024-08-06
Healthy Volunteers
No
Conditions
Interventions
Control Group
sleep hygiene education
Surgical Intervention
Surgical Intervention includes uvulopalatopharyngoplasty (UPPP) and transoral robotic surgery (TORS). UPPP involves the removal of the uvula and tonsils, while TORS consists of the removal of the uvula, tonsils, and adipose tissue at the base of the tongue.
Oropharyngeal Training (face-to-face)
Participants will attend face-to-face oropharyngeal training sessions with a therapist in the lab, each lasting 45-60 minutes, 1-2 times per week, over a 12-week intervention period.
Oropharyngeal Training (telerehabilitation)
Participants will attend online oropharyngeal training (telerehabilitation) sessions with a therapist, each lasting 45-60 minutes, 1-2 times per week, over a 12-week intervention period.
Continuous Positive Airway Pressure
Participants will use Continuous Positive Airway Pressure (CPAP) throughout the intervention period.
Locations (1)
National Cheng Kung University Hospital
Tainan, Taiwan