Clinical Research Directory
Browse clinical research sites, groups, and studies.
Role of Topical Steroid Injection With Refractory Benign Esophageal Stricture Endoscopic Dilatation in Children
Sponsor: Mohammad Daboos
Summary
This clinical trial study included 21 children with refractory benign esophageal strictures. Upper GI endoscopy performed up to the area of stricture, esophageal dilatation done, endoscopy repeated, and steroid injected intralesional under direct endoscopic vision. The effect of the procedure was followed over a period of 12 months by evaluation of number of dilatation, maximum dilator size, periodic dilatation index (PDI) and dysphagia score.
Key Details
Gender
All
Age Range
2 Years - 14 Years
Study Type
INTERVENTIONAL
Enrollment
21
Start Date
2022-03-02
Completion Date
2024-08-20
Last Updated
2024-07-23
Healthy Volunteers
No
Interventions
Esophageal dilatation with steroids injection
Under general anesthesia with the patient in the left lateral position. A single-channel endoscope was used. Endoscopic bougie dilatation was performed using Wire-guided Polyvinyl dilator Savary Gilliard/SG. Long-acting steroids triamcinolone acetonide was injected via 25-gauge sclerotherapy catheter. One mL solution of triamcinolone acetonide 40mg/ml was diluted with one mL of saline, in a 2 mL disposable syringe, and 0.5 mL each was injected at the proximal margin of the stricture in four quadrants, 2 mL solution in four quadrants
Locations (1)
Mohammad Daboos
Cairo, Select, Egypt