Clinical Research Directory

Inclusion Criteria: * Age\>=18 years * HIV Diagnosis * On Antiretroviral Therapy with HIV Viral Load\<200 within last year Exclusion Criteria: * Other significant immunosuppressing condition * Age\< 18 years * Pregnancy (at enrollment) * Contraindication to pneumococcal vaccination * Known contraindication to non-clinical blood draws (severe anemia last hemoglobin \<8g/dl) * Subjects who, in the opinion of the Investigator, may be non-adherent to study schedules or procedures. * Adults unable to consent * Individuals with impaired ability to consent * Incarceration at time of enrollment Controls inclusion criteria: * Age\>=18 years * HIV Ag-Ab test negative