Clinical Research Directory

Inclusion Criteria: Comprehensive examination and analysis of imaging, laboratory examination and other comprehensive examinations, the diagnosis is clear, which is in line with lobe resection surgical indications Age 18-75 years old, the gender is not limited; ASA grading Ⅰ \~ III level; It is expected that the single lung ventilation time is ≥1 hours, and ≤3 hours Exclusion Criteria: Emergency surgery; There is a taboos on the existence of systemic anesthesia; There is a history of acute chronic upper respiratory infections in the past January; Previous bronchial asthma, chronic obstructive pulmonary disease, bronchial dilatation, phthisis ,aspergillosis , acute respiratory distress syndrome or history of respiratory failure; Merge the function of important organs such as heart, liver, and kidney; There was a history of chest surgery and the history of trauma; Preoperative lung function test obvious abnormal abnormal abnormalities (1 second of exhalation (FEV1) \<60%); Patients refuse to participate in the clinical trial