Clinical Research Directory

Inclusion Criteria: 1. Signs and symptoms of HF according to the Europeans Society of Cardiology guideline. 2. LV ejection fraction ≥40%. 3. HFA-PEFF score ≥5 or HFA-PEFF score 2-4 in combination with positive stress test (Figure 1). 4. \>18 years of age 5. In sinus rhythm 6. Able to perform a bicycle exercise test 7. Willing to sign informed consent Exclusion Criteria: 1. Body weight \>140 kg 2. Atrial fibrillation or other significant arrhythmia during the assessment 3. Contraindications for CMR (e.g. claustrophobia, implanted cardiac devices) 4. Myocardial infarction, percutaneous coronary intervention or coronary artery bypass graft \<3 months or untreated severe obstructive coronary artery stenosis 5. More than moderate left-sided valve disease. 6. Complex congenital heart disease.