Clinical Research Directory

Inclusion Criteria: * Subjects must meet all of the following criteria to be enrolled: 1. Male or female, aged ≥18 years; 2. Patients with various types of pneumothorax who still have persistent air leaks after continuous intercostal drainage for 7 days; 3. After evaluation by the researcher, the subject is feasible for the bronchoscopic procedure of selective bronchial occlusion to treat refractory pneumothorax, and the responsible bronchus can be determined by the balloon detection; 4. Voluntarily participate in this trial and sign an informed consent form. Exclusion Criteria: * Subjects with any of the following conditions cannot be selected: 1. Allergic to silicone materials; 2. Contraindications for bronchoscopy: * Myocardial infarction within the past month; * Active massive hemoptysis; * Platelet count \<20×10\^9/L; * Pregnancy; * Malignant arrhythmias, unstable angina, severe cardiopulmonary dysfunction, hypertensive crisis, severe pulmonary arterial hypertension, intracranial hypertension, acute cerebrovascular events, aortic dissection, aortic aneurysm, severe mental illness, and extreme systemic exhaustion, etc. 3. Uncontrolled acute pulmonary infection or severe chronic infection at the intended occlusion lobes or segments; 4. Obvious hemodynamic instability or unstable respiratory failure; 5. The responsible bronchus cannot be determined by balloon detection; 6. The researcher believes that the patient has other conditions that are not suitable for inclusion in this study.