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RECRUITING
NCT06515210
NA

Personalized Anti-Inflammatory Fibres in Ulcerative Colitis

Sponsor: University of Alberta

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to determine the clinical effects of two different dietary fibre supplements, acacia gum (AG) and microcrystalline cellulose (MCC), in patients with ulcerative colitis. The main question it aims to answer is: Can the fibre supplements reduce gut inflammation (fecal calprotectin)? Researchers will compare AG and MCC to a placebo (a look-alike substance that contains no fibre) to see if the fibre supplements improve inflammation in ulcerative colitis. Participants will add their assigned fibre supplement or placebo to their usual diet daily for 6 weeks. They will visit the clinic at baseline, week 3, and week 6 to provide samples (stool, blood) and complete various questionnaires.

Official title: Clinical Profiling of Anti-inflammatory Fibre Supplements in Patients With Ulcerative Colitis: Towards Personalized Complementary Strategies.

Key Details

Gender

All

Age Range

15 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

69

Start Date

2025-06-03

Completion Date

2026-12

Last Updated

2025-06-10

Healthy Volunteers

No

Interventions

DIETARY_SUPPLEMENT

Acacia Gum

Participants (n=23) incorporate the fibre supplement into their usual diet daily.

DIETARY_SUPPLEMENT

Microcrystalline Cellulose

Participants (n=23) incorporate the fibre supplement into their usual diet daily.

DIETARY_SUPPLEMENT

Placebo

Participants (n=23) incorporate the placebo into their usual diet daily.

Locations (1)

University of Alberta Hospital

Edmonton, Alberta, Canada