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Personalized Anti-Inflammatory Fibres in Ulcerative Colitis
Sponsor: University of Alberta
Summary
The goal of this clinical trial is to determine the clinical effects of two different dietary fibre supplements, acacia gum (AG) and microcrystalline cellulose (MCC), in patients with ulcerative colitis. The main question it aims to answer is: Can the fibre supplements reduce gut inflammation (fecal calprotectin)? Researchers will compare AG and MCC to a placebo (a look-alike substance that contains no fibre) to see if the fibre supplements improve inflammation in ulcerative colitis. Participants will add their assigned fibre supplement or placebo to their usual diet daily for 6 weeks. They will visit the clinic at baseline, week 3, and week 6 to provide samples (stool, blood) and complete various questionnaires.
Official title: Clinical Profiling of Anti-inflammatory Fibre Supplements in Patients With Ulcerative Colitis: Towards Personalized Complementary Strategies.
Key Details
Gender
All
Age Range
15 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
69
Start Date
2025-06-03
Completion Date
2026-12
Last Updated
2025-06-10
Healthy Volunteers
No
Conditions
Interventions
Acacia Gum
Participants (n=23) incorporate the fibre supplement into their usual diet daily.
Microcrystalline Cellulose
Participants (n=23) incorporate the fibre supplement into their usual diet daily.
Placebo
Participants (n=23) incorporate the placebo into their usual diet daily.
Locations (1)
University of Alberta Hospital
Edmonton, Alberta, Canada