Clinical Research Directory
Browse clinical research sites, groups, and studies.
Texture and Colour Enhancement Imaging in Improving Detection and Miss Rate of Premalignant Lesions
Sponsor: Changhai Hospital
Summary
Texture and Color Enhancement Imaging (TXI) is a newly developed image-enhancing endoscopy technology that has show potential in improving detection of colorectal lesions. This multicenter, randomized, tandem trial is aimed at evaluating whether TXI is superior to WLI endoscopy in terms of diagnosis of premalignant lesions.
Official title: Impact of Texture and Color Enhancement Imaging on Detection and Miss Rate of Premalignant Lesions: A Multicentre, Randomized, Tandem Trial
Key Details
Gender
All
Age Range
45 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
2964
Start Date
2024-08-01
Completion Date
2025-08-01
Last Updated
2024-07-23
Healthy Volunteers
No
Conditions
Interventions
TXI (Group A)
Patients in Group A will undergo colonoscopy with TXI.
TXI followed by WLI (Group B)
Patients in group B will first undergo colonoscopy with TXI and every polyp found should be removed. Then switch to WLI for a second withdrawal to detect lesions that were not observed the first time.
WLI (Group C)
Patients in Group C will undergo colonoscopy with WLI.
WLI followed by TXI (Group D)
Patients in group D will first undergo colonoscopy with WLI and every polyp found should be removed. Then switch to TXI for a second withdrawal to detect lesions that were not observed the first time.