Clinical Research Directory

Inclusion Criteria: 1. Age 18-85 years old, gender unlimited; 2. The diagnosis was obstructive hypertrophic cardiomyopathy. 3. Echocardiographic laboratory tests showed LVEF≥60%; 4. No previous left ventricular systolic dysfunction at any time (LVEF \< 45%); 5. Understand the study procedure and sign the informed consent in person, willing to strictly follow the clinical study protocol to complete the study. Exclusion Criteria: 1. Known or suspected invasive, genetic or storage diseases (e.g. Noonan syndrome, Fabre's disease, amyloidosis) that cause cardiac hypertrophy (similar to oHCM); 2. Previous left ventricular systolic dysfunction at any time in the clinical course (LVEF \< 45%); 3. Previous history of aortic stenosis or subaortic fixed stenosis;