Clinical Research Directory

Inclusion Criteria: 1. Patients With ECOG Score 0-1 Points 2. Patients With Breast Cancer Stage cT1-3N1M0 (According to AJCC Version 7) Pathological Diagnosis of Ipsilateral Axillary Lymph Node Metastasis in Patients With Invasive Breast Cancer 3. Patients With Abnormal Axillary Lymph Nodes ≤ 3 Detected by Imaging Examination 4. Patients With Effective Neoadjuvant Therapy (CR+PR) 5. Patients With Clinical Axillary Negative ycN0 After Neoadjuvant Therapy 6. Patients Without Prior History of Ipsilateral Axillary Surgery and Radiation Therapy 7. Patients Without Previous History of Ipsilateral Breast Cancer (Including Carcinoma in Situ) 8. Patients Without Obvious Contraindications for Surgery or Radiation Therapy 9. No Other History of Malignant Tumors Within 5 Years From Enrollment in the Study 10. Patients Who Participate in Other Clinical Trials at the Same Time and Are Judged by the Researchers Not to Affect the Study Protocol Can be Enrolled Normally 11. The patient voluntarily joined this study and signed an informed consent form. Exclusion Criteria: 1. Stage IV (metastatic) breast cancer； 2. Simultaneous double breast cancer； 3. Baseline cT4; 4. Baseline cN2-3 5. gestation 6. There are contraindications for SLNB; 7. Suffering from serious comorbidities or other comorbidities that may interfere with the planned treatment, or any other circumstances in which the researcher deems the patient unsuitable to participate in this study