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NCT06518512

Automated Vision Assessment and Impairment Detection Through Gaze Analysis in Wet AMD Patients

Sponsor: Tan Tock Seng Hospital

View on ClinicalTrials.gov

Summary

The study aims to evaluate the Automated Vision Assessment and Impairment Detection through Gaze Analysis (AVIGA) system in the ability to detect and assess central vision dysfunction in a personalized, adaptive, objective, and automated way through eye gaze tracking in age-related macular degeneration (AMD). We also aim to develop a novel algorithm / scoring methodology for disease activity monitoring over time (delta-change). AVIGA visual risk prediction cut-off scores will be presented together with probabilities of occurrence of prespecified adverse clinical outcome.

Official title: Automated Vision Assessment and Impairment Detection Through Gaze Analysis in Wet Age Related Macular Degeneration (AMD) Patients: a Prospective Clinical Evaluation (AVIGA2)

Key Details

Gender

All

Age Range

55 Years - Any

Study Type

OBSERVATIONAL

Enrollment

128

Start Date

2023-04-18

Completion Date

2026-12

Last Updated

2026-01-08

Healthy Volunteers

No

Interventions

DEVICE

Automated Vision Assessment and Impairment Detection through Gaze Analysis (AVIGA) system

AVIGA is an automated method and system for vision assessment of a subject. The method includes the following: determining a set of test patterns for the subject based on a preliminary assessment of an eye of the subject; displaying the set of test patterns sequentially to the subject; collecting data on the subject's gaze in response to each test pattern displayed; and correlating central vision function of the subjects to the collected gaze data. Subjects perform the AVIGA test monocularly and pursue a pre-determined target moving in a customized waveform across the computer screen. The trail of the gaze points generated by the subject following the target is simultaneously recorded and stored. 1. Static Fixation Evaluation (SFE) 2. Static Perimetry Assessment (SPA) 3. Static Perimetry Sensitivity Assessment (SPSA) 4. Pursuit

Locations (1)

Tan Tock Seng Hospital

Singapore, Singapore