Clinical Research Directory

Inclusion criteria: Part 1 Clinical characteristics of small intestinal bacterial overgrowth in patients with abdominal distension of different etiologies 1. Age 18-60 years old and gender; 2. The chief complaint is abdominal distension and/or abdominal distension, abdominal distension and/or abdominal distension more prominent than other symptoms. Part 2 Efficacy observation of functional abdominal distention combined with small intestine bacterial overgrowth 1. Patients with functional abdominal distension and small intestinal bacterial overgrowth were selected in Part 1; 2. No drug contraindications. Exclusion criteria: Part 1 Clinical characteristics of small intestinal bacterial overgrowth in patients with abdominal distension of different etiologies 1. Preparation for pregnancy, pregnancy, breastfeeding women, or overall poor compliance, or other conditions that the investigator believes need to be excluded; 2. History of malignant tumors, history of abdominal surgeries; 3. Food intolerance, confirmed or suspected lactose intolerance; 4. Diagnosis of urinary system (chronic kidney disease, etc.), immune system (scleroderma, etc.), nervous system (Parkinson's disease, etc.), mental system (depression, etc.) and other diseases outside the digestive system; 5. Antibiotics and microecological preparations should be used within two weeks. Use motility enhancers, secretagogues, antifoaming agents, spasmolytics, opioids, antidepressants and other medications within a week. Part 2 Efficacy observation of functional abdominal distention combined with small intestine bacterial overgrowth 1. Antibiotics and microecological preparations should be used within two weeks; 2. Use motility enhancers, secretagogues, antifoaming agents, spasmolytics, opioids, antidepressants and other medications within a week.