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Study of Infantile Lower Limb Malformations and Deformities
Sponsor: Istituto Ortopedico Rizzoli
Summary
The skeletal defects of the lower limbs in pediatric age encompass various congenital and acquired conditions that alter bone structure. These alterations can be symmetrical or asymmetrical, with potential consequences such as deformities, short stature, and disability. These condictions may impact not only on the physical and the mental function of the children, but also on their family context. Management often requires a multidisciplinary approach for early diagnosis and treatment. Deformities are heterogeneous and necessitate a personalized therapeutic plan. Currently, in pediatric orthopedic surgery there is a lack of an instrument capable of evaluating all these aspects. The advancement of computer-assisted surgery and artificial intelligence could improve treatment customization and involve patients and families in therapeutic decision-making to prevent complications. This study aims to provide support for clinical practice to promote a systematic, comprehensive, and sequential evaluation of lower limb deformities in developmental age, from which epidemiological data and evidence on treatment approaches used in major referral centers can be extrapolated.
Official title: Observational Retrospective and Prospective Study of Infantile Lower Limb Malformations and Deformities
Key Details
Gender
All
Age Range
Any - 18 Years
Study Type
OBSERVATIONAL
Enrollment
1000
Start Date
2024-10-31
Completion Date
2029-05
Last Updated
2025-12-26
Healthy Volunteers
No
Conditions
Interventions
Conservative treatment
Patients are provided with physiotherapy support and the provision of prostheses with the goal of ensuring as much walking functionality as possible.
Single or multi-stage surgery
Correction of the deformity is pursued by one or more surgical procedures with the timing and the techniques (growth modulation, acute correction, gradual correction, soft tissues procedures, combined techniques) chosen according to the surgeon's preference to achieve the maximum possible walking functionality without orthopedic aids.
Amputation
Limb surgery, whether or not associated with realignment or soft-tissue surgery, is performed, aimed at providing the maximum possible walking function through a prosthesis.
Locations (7)
IRCCS Istituto Ortopedico Rizzoli
Bologna, Italy
Istituto Giannina Gaslini
Genova, Italy
Galeazzi Orthopedic Institute
Milan, Italy
Policlinico San Matteo
Pavia, Italy
Istituto Nazionale Tumori Regina Elena
Roma, Italy
Ospedale Pediatrico Bambino Gesù
Roma, Italy
Istituto Clinico Humanitas
Rozzano, Italy