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RECRUITING
NCT06519422
PHASE3

Tranexamic Acid for Anaemia Trial

Sponsor: London School of Hygiene and Tropical Medicine

View on ClinicalTrials.gov

Summary

Anaemia is when the body does not have enough healthy red blood cells to carry oxygen. It is common in women because they lose blood every month during their periods. Anaemia can womwn make feel tired, weak, dizzy and out of breath. It can also make it harder to study, work or look after their family. If woman become pregnant with anaemia, it can cause problems for both mother and baby, such as early birth or heavy bleeding when giving birth. It is best to treat anaemia in young women well before they get pregnant. Doctors treat anaemia with iron and vitamins. But some people get side effects when taking iron tablets and so they stop taking them. Tranexamic acid (TXA) is a medicine used to treat heavy periods. The investigators of this study would like to find out if taking TXA with the usual iron and vitamin supplements is better at treating anaemia than taking iron and vitamin supplements alone. (Lay Summary)

Official title: The Effects of Tranexamic Acid on Anaemia, Menstrual Health and the Wellbeing of Women: an International Randomised, Placebo-controlled Trial Among Menstruating Women With Anaemia

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

4000

Start Date

2026-08-10

Completion Date

2028-09

Last Updated

2026-08-17

Healthy Volunteers

No

Conditions

Interventions

DRUG

Tranexamic Acid 500 MG

Tablets

DRUG

Placebo

Tablets

Locations (3)

University College Hospital

Ibadan, Oyo State, Nigeria

Shifa Tameer e Millat University

Islamabad, Pakistan

Mbeya College of Health and Allied Sciences, University of Dar es Salaam

Mbeya, Tanzania