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Tranexamic Acid for Anaemia Trial
Sponsor: London School of Hygiene and Tropical Medicine
Summary
Anaemia is when the body does not have enough healthy red blood cells to carry oxygen. It is common in women because they lose blood every month during their periods. Anaemia can womwn make feel tired, weak, dizzy and out of breath. It can also make it harder to study, work or look after their family. If woman become pregnant with anaemia, it can cause problems for both mother and baby, such as early birth or heavy bleeding when giving birth. It is best to treat anaemia in young women well before they get pregnant. Doctors treat anaemia with iron and vitamins. But some people get side effects when taking iron tablets and so they stop taking them. Tranexamic acid (TXA) is a medicine used to treat heavy periods. The investigators of this study would like to find out if taking TXA with the usual iron and vitamin supplements is better at treating anaemia than taking iron and vitamin supplements alone. (Lay Summary)
Official title: The Effects of Tranexamic Acid on Anaemia, Menstrual Health and the Wellbeing of Women: an International Randomised, Placebo-controlled Trial Among Menstruating Women With Anaemia
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
4000
Start Date
2026-08-10
Completion Date
2028-09
Last Updated
2026-08-17
Healthy Volunteers
No
Conditions
Interventions
Tranexamic Acid 500 MG
Tablets
Placebo
Tablets
Locations (3)
University College Hospital
Ibadan, Oyo State, Nigeria
Shifa Tameer e Millat University
Islamabad, Pakistan
Mbeya College of Health and Allied Sciences, University of Dar es Salaam
Mbeya, Tanzania