Clinical Research Directory

Inclusion Criteria: * Body mass index equal or above 27.5 kg/m2 (26.0 kg/m2 for those of Asian descent) * Eating home-made meals at least 5 days a week * Physically and mentally fit as assessed by the study researcher * On-going pharmacological and hormonal treatment is accepted when this does not affect the study parameters (e.g. glucose response, appetite), and when the participant has been in a stable dose for at least 3 months * Agreeing to undergo all the study procedures * Being able to attend in person on 3 clinical investigation days during working hours * Being able to understand and agree to sign the informed consent form Exclusion Criteria: * Being a regular smoker (that is, smoke more than 4 cigarettes a month) * Being pregnant, breastfeeding or planning a pregnancy * Exceed the alcohol consumption limit marked for the corresponding sex (more than 14 units in women and 20 units in men) * Having followed a meal plan for weight loss and/or muscle mass gain in the 3 months prior to the start of the study intervention * Having used a portion measuring instrument (e.g. scale, calibrated plate, etc.) consistently (at least in one main meal for at least 5 days a week) during the 3 months prior to the start of the study intervention * Experiencing a weight change greater than 5% in the last 3 months * History of relevant functional or structural anomalies of the digestive system, such as malformations, angiodysplasias, active peptic ulcers, chronic inflammatory or malabsorption diseases, or history of intestinal or bariatric surgery * Suffer from some type of cancer, currently undergoing treatment for cancer, or when a period of at least 5 years has not elapsed since its eradication * On-going chronic metabolic disease or obesity-related disease, or any systemic intestinal, liver or kidney disease such as type 1 or type 2 diabetes, severe dyslipidemia, uncontrolled thyroid function disorder, cirrhosis, inflammatory bowel disease, untreated anemia, etc. . (will not be excluded due to "fatty liver") * Avoiding, being allergic, or being intolerant to the study foods or their ingredients (lactose free and regular chocolate milkshake) * History of anaphylactic reaction to any food * Taking any nutritional supplementation as a prescription medication that may affect the results of the study * Taking over-the-counter nutritional supplementation (that is, without a medical prescription) that may affect the results of the study, unless the person is willing to stop it during the 6 months of the study duration and only when a minimum washout period of 14 days can be guaranteed prior to the basal measurements being taken * A high incidence of attitudes and behaviors associated with eating disorders, expressed as a score greater than 20 on the 26-item Eating Attitudes Test scale (EAT - 26) * Co-inhabiting with a study participant * For former PORTIONS-3 study participants, when less than 3 months have passed since the last intervention visit (accepted if 3 or more months have elapsed).