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Optimal Articular Solutions With Intraosseous and Synovial Platelet-Rich Plasma
Sponsor: Universidade do Porto
Summary
This is a prospective cohort clinical study. Due to logistic constraints at the sites of implementation, a randomized allocation will not be feasible (private clinic). Patients will be selected with the aim of matching for important confounders (sex and age) the grade of knee OA will be restricted to advance stages.
Official title: Comparison of Efficacy of Intraosseous vs Intra-articular Injections of PRP for Advanced Knee OA
Key Details
Gender
All
Age Range
45 Years - Any
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2025-01-01
Completion Date
2027-10-31
Last Updated
2024-08-06
Healthy Volunteers
No
Conditions
Interventions
Platelet rich-plasma - PRP - intraosseous and intra-articular admnistration
Group 1 will receive two intraosseous injections of PRP and a subsequent/synchronous intra-articular injection of PRP on the same day. Group 2 will only receive two intra-articular injections of PRP, separated by one week.
Locations (2)
Faculdade de Medicina da Universidade do Porto
Porto, Portugal
Faculdade de Medicina da Universidade do Porto
Porto, Portugal