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Investigating the Functional Characteristics During Wakefulness and Sleep Based on SEEG
Sponsor: Xuanwu Hospital, Beijing
Summary
This study aims to collect electrophysiological and clinical data from patients aged 14-65 with drug-resistant epilepsy who underwent SEEG. The collected data will be analyzed to investigate the functional connectivity during wakefulness and sleep states.
Key Details
Gender
All
Age Range
14 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2024-07-08
Completion Date
2027-10-08
Last Updated
2025-06-27
Healthy Volunteers
No
Conditions
Interventions
SEEG recordings and SPES
This study will utilize stereoelectroencephalography (SEEG) recordings combined with single-pulse electrical stimulation (SPES) to investigate functional brain connectivity and cortical excitability patterns in patients with epilepsy during both wakefulness and sleep states. The SEEG recordings will provide high-resolution intracranial electrophysiological data, while SPES will be employed to actively probe and quantify cortico-cortical connections. This combined approach will enable characterization of state-dependent neural network dynamics.
Locations (1)
Xuanwu Hospital, Beijing
Beijing, Beijing Municipality, China