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RECRUITING
NCT06524531
EARLY_PHASE1

Pulsed RF Neuromodulation and Leukocyte-Rich PRP for Refractory Low Back Pain

Sponsor: Iffat Anwar Medical Complex

View on ClinicalTrials.gov

Summary

This clinical trial aims to check the safety and efficacy profile of pulsed radiofrequency (RF) neuromodulation combined with leukocyte-rich platelet-rich plasma (PRP) injections for the treatment of refractory low back pain due to multifidus dysfunction. The trial will compare two groups: one receiving standard physical therapy and the other receiving pulsed RF neuromodulation and physiotherapy.

Official title: Safety and Efficacy of Pulsed RF Neuromodulation and Leukocyte-Rich PRP for the Treatment of Refractory Low Back Pain Due to Multifidus Dysfunction

Key Details

Gender

All

Age Range

30 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2024-07-10

Completion Date

2025-12-30

Last Updated

2024-09-19

Healthy Volunteers

No

Interventions

PROCEDURE

Pulsed RF Neuromodulation

RF neuromodulation will be applied to the L2 and L3 segments bilaterally. Each segment will receive treatment for 6 minutes, either sequentially or simultaneously on both sides.

BIOLOGICAL

Leukocyte-Rich PRP Injection

Leukocyte-rich PRP will be prepared from the patient's blood and injected into the multifidus muscle at the L2 and L3 levels.

PROCEDURE

Physiotherapy Alone

Standard physiotherapy regimen tailored to each participant's needs. This may include exercises to improve flexibility, strength, and endurance of the back muscles, as well as education on posture and body mechanics.

Locations (1)

Iffat Anwar Medical Complex

Lahore, Punjab Province, Pakistan