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NOT YET RECRUITING
NCT06527079

Evaluation of Clinical Decision Support in Opioid Tapering

Sponsor: University of Colorado, Denver

View on ClinicalTrials.gov

Summary

The 2022 Center for Disease Control and Prevention (CDC) clinical practice guideline for prescribing opioids for pain recommends that when tapering a patient's opioid dose, doses should be decreased at a slow rate to reduce the risk of withdrawal symptoms, overdose, and to promote tolerance of the tapering. This project will evaluate a clinical decision support (CDS) tool in the form of a clinical care pathway that gives providers information, recommendations, and educational material on strategies for opioid tapering. Primary care providers will be randomized at the clinic location to a control arm or intervention arm. The control arm will have the clinical care pathway available, but will not be reminded of the pathway when tapering a patient. The intervention arm will receive a nudge when prescribing a tapering opioid strategy to a patient to use the clinical care pathway. The rate of opioid tapering in line with CDC guidelines will be examined as well as long-term patient outcomes of opioid overdose or poisoning using existing patient health records. The study period will be approximately 18 months.

Key Details

Gender

All

Age Range

12 Years - 89 Years

Study Type

OBSERVATIONAL

Enrollment

200000

Start Date

2026-02

Completion Date

2027-06

Last Updated

2025-12-10

Healthy Volunteers

Yes

Interventions

OTHER

Opioid Tapering Pathway Clinical Decision Support (CDS)

Clinical decision support in the form of an electronic health record (EHR)-integrated, provider facing notification suggesting the provider utilize a clinical care pathway that provides resources and decision support in opioid tapering in line with CDC guidelines.