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Curcumin and EGCG Supplementation to Improve Serum BDNF and Mood Disturbance
Sponsor: Auburn University
Summary
The goal of this randomized placebo controlled trial is to examine mood disturbance and serum brain derived neurotrophic factor (BDNF) in people (age 18-50) with DASS-21 subscale scores \>9. The main questions it aims to answer are: Does curcumin and EGCG supplementation improve mood disturbance symptomology? Does curcumin and EGCG supplementation increase serum BDNF? Researchers will compare intervention versus placebo. Participants will consume an 8-week supplement of both: * 1,330mg/day curcumin * 350mg/day epigallocatechin gallate (EGCG)
Official title: A Randomized Controlled Trial to Determine the Effects of Curcumin and Epigallocatechin Gallate Supplementation on Serum Brain Derived Neurotrophic Factor and Mood Disturbance in Adults
Key Details
Gender
All
Age Range
18 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
64
Start Date
2024-09-30
Completion Date
2025-08-01
Last Updated
2025-02-14
Healthy Volunteers
Yes
Conditions
Interventions
Curcumin
1,330 mg curcumin
Epigallocatechin Gallate
350 mg Epigallocatechin gallate (EGCG)
Placebo
Placebo to be consumed after randomization.
Locations (1)
Auburn University School of Kinesiology
Auburn, Alabama, United States