Clinical Research Directory
Browse clinical research sites, groups, and studies.
Gut Microbiota in Chronic GI Diseases
Sponsor: McMaster University
Summary
The study involves characterizing the microbiota of patients with IBS, functional diarrhea, IBD, severe motility disorders and celiac disease. This will be complemented by a translational phase of human-mouse hybrid experiments in which germ-free mice will be colonized with feces from these patients with different GI disease and non-disease controls and we will compare symptoms, microbiota composition and histological changes in the gut and in the brain of the mice.
Official title: The Role of Gut Microbiota in Chronic GI Diseases: A Pilot Study
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
OBSERVATIONAL
Enrollment
260
Start Date
2012-10-01
Completion Date
2026-11-01
Last Updated
2024-08-01
Healthy Volunteers
Yes
Conditions
Interventions
Endoscopy/Colonoscopy
Esophagogastroduodenoscopy and colonoscopy with video recording and biopsy collection
Locations (1)
McMaster University
Hamilton, Ontario, Canada